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VM Quetiapine

Visual representation of the interaction
Mode of action
Transporter zone
Important for clinical effects
Enzyme zone
No interaction
Receptor zone
Contributes to other effects
Contributes to other effects
Important for clinical effects
Important for clinical effects
Important for clinical effects
Important for clinical effects
Ion channel zone
No interaction

NbN-2 quetiapine

Molecular structure
NbN_library N O N N S OH
Mode of action
receptor antagonist (D2, 5-HT2) and reuptake inhibitor (NET)(metabolite)
Pharmacological target
dopamine, serotonin
Date published


For more detailed explanation of the principles of the VM Library
For more detailed explanation of the Neuroscience based Nomenclature

Please notice that Caution should be applied when extrapolating animal data to humans.

Detailed and Approved Information on the clinical use of the compounds can be found at the homepage of EMA or at Martindale.

  1. Richelson, E. and T. Souder (2000). "Binding of antipsychotic drugs to human brain receptors focus on newer generation compounds." Life Sci 68(1): 29-39.
  2. Sato, H., C. Ito, K. Hiraoka, M. Tashiro, K. Shibuya, Y. Funaki, T. Yoshikawa, R. Iwata, H. Matsuoka and K. Yanai (2015). "Histamine H1 receptor occupancy by the new-generation antipsychotics olanzapine and quetiapine: a positron emission tomography study in healthy volunteers." Psychopharmacology (Berl) 232(19): 3497-3505.
  3. Nyberg, S., J. A, T. A, K. M, C. Z, H. C and L. Farde (2013). "Norepinephrine transporter occupancy in the human brain after oral administration of quetiapine XR." Int J Neuropsychopharmacol 16(10): 2235-2244.
  4. NbN-2
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