Understanding the pathology of Parkinson's disease

Parkinson’s disease is the second most frequent neurodegenerative disorder of aging after Alzheimer’s disease. Parkinson’s disease is characterized by 4 cardinal motor symptoms: tremor at rest; rigidity; bradykinesia; and postural instability. This progressive disorder is also associated with cognitive, behavioural, and autonomic impairments causing increased disability and contributing to a loss of independence.

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