Chlorpromazine

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Mode of action
Chlorpromazine
Transporter zone
Contributes to other effects
Enzyme zone
No interaction
Receptor zone
Contributes to other effects
Contributes to other effects
Important for clinical effects
Important for clinical effects
Contributes to other effects
Ion channel zone
No interaction
References
  1. Roth, B. L., S. C. Craigo, M. S. Choudhary, A. Uluer, F. J. Monsma, Jr., Y. Shen, H. Y. Meltzer and D. R. Sibley (1994). "Binding of typical and atypical antipsychotic agents to 5-hydroxytryptamine-6 and 5-hydroxytryptamine-7 receptors." J Pharmacol Exp Ther 268(3): 1403-1410.
  2. Tatsumi, M., K. Jansen, R. D. Blakely and E. Richelson (1999). "Pharmacological profile of neuroleptics at human monoamine transporters." Eur J Pharmacol 368(2-3): 277-283.
  3. Trichard, C., M. L. Paillere-Martinot, D. Attar-Levy, C. Recassens, F. Monnet and J. L. Martinot (1998). "Binding of antipsychotic drugs to cortical 5-HT2A receptors: a PET study of chlorpromazine, clozapine, and amisulpride in schizophrenic patients." Am J Psychiatry 155(4): 505-508.

For more detailed explanation of the principles of the VM Library

Please notice that Caution should be applied when extrapolating animal data to humans.

Detailed and Approved Information on the clinical use of the compounds can be found at the homepage of EMA or at Martindale.

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