Rivastigmine

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Mode of action
Rivastigmine
Transporter zone
No interaction
Enzyme zone
Butyrylcholinesterase
Acetylcholinesterase
Receptor zone
No interaction
Ion channel zone
No interaction
References
  1. Luo W, Yu QS, Kulkarni SS, et al. (2006) Inhibition of human acetyl- and butyrylcholinesterase by novel carbamates of (-)- and (+)-tetrahydrofurobenzofuran and methanobenzodioxepine. J Med Chem 49: 2174-2185.
  2. Deardorff WJ, Feen E and Grossberg GT. (2015) The Use of Cholinesterase Inhibitors Across All Stages of Alzheimer's Disease. Drugs Aging 32: 537-547.
  3. Ali TB, Schleret TR, Reilly BM, et al. (2015) Adverse Effects of Cholinesterase Inhibitors in Dementia, According to the Pharmacovigilance Databases of the United-States and Canada. PLoS One 10: e0144337.

For more detailed explanation of the principles of the VM Library

Please notice that Caution should be applied when extrapolating animal data to humans.

Detailed and Approved Information on the clinical use of the compounds can be found at the homepage of EMA or at Martindale.

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