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Mode of action
Pimozide
Transporter zone
No interaction
Enzyme zone
No interaction
Receptor zone
Important for clinical effects
Important for clinical effects
Contributes to other effects
Contributes to other effects
Important for clinical effects
Ion channel zone
No interaction
References
  1. Kongsamut S, Kang J, Chen XL, et al. (2002) A comparison of the receptor binding and HERG channel affinities for a series of antipsychotic drugs. Eur J Pharmacol 450: 37-41.
  2. Mothi M and Sampson S. (2013) Pimozide for schizophrenia or related psychoses. Cochrane Database Syst Rev: CD001949.
  3. Richelson E and Souder T. (2000) Binding of antipsychotic drugs to human brain receptors focus on newer generation compounds. Life Sci 68: 29-39.

For more detailed explanation of the principles of the VM Library

Please notice that Caution should be applied when extrapolating animal data to humans.

Detailed and Approved Information on the clinical use of the compounds can be found at the homepage of EMA or at Martindale.

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