Amisulpride

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Mode of action
Amisulpride
Transporter zone
No interaction
Enzyme zone
No interaction
Receptor zone
Important for clinical effects
Contributes to other effects
Ion channel zone
No interaction
References
  1. Abbas AI, Hedlund PB, Huang XP, et al. (2009) Amisulpride is a potent 5-HT7 antagonist: relevance for antidepressant actions in vivo. Psychopharmacology (Berl) 205: 119-128.
  2. Lako IM, van den Heuvel ER, Knegtering H, et al. (2013) Estimating dopamine D(2) receptor occupancy for doses of 8 antipsychotics: a meta-analysis. J Clin Psychopharmacol 33: 675-681.
  3. Trichard C, Paillere-Martinot ML, Attar-Levy D, et al. (1998) Binding of antipsychotic drugs to cortical 5-HT2A receptors: a PET study of chlorpromazine, clozapine, and amisulpride in schizophrenic patients. Am J Psychiatry 155: 505-508.
  4. Vancampfort D, Correll CU, Galling B, et al. (2016) Diabetes mellitus in people with schizophrenia, bipolar disorder and major depressive disorder: a systematic review and large scale meta-analysis. World Psychiatry 15: 166-174.

For more detailed explanation of the principles of the VM Library

Please notice that Caution should be applied when extrapolating animal data to humans.

Detailed and Approved Information on the clinical use of the compounds can be found at the homepage of EMA or at Martindale.

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