Synaptic Dopamine reuptake and degradation

Dopamine is released from the presynaptic terminal, diffuses over the synaptic cleft and activates Dopaminergic receptors ( D1 or D2 receptors). After dissociation from the receptor, Dopamine is taken up up via a presynaptically located Dopamine transporter and degraded by the Mono amine oxidase B ( MAO-B)

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